Aloxistatin
An irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets; reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B.Other Indication Discontinued.
Product Specifications
CAS Number
88321-09-9
Product Name Alternative
E64 d | Loxistatin | Rexostatine
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 23 mg/mL
Smiles
CCOC ([C@@H]1[C@@H] (C (N[C@H] (C (NCCC (C) C) =O) CC (C) C) =O) O1) =O
Molecular Formula
C17H30N2O5
Molecular Weight
342.4305
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Oxiranecarboxylic acid, 3-[[[ (1S) -3-methyl-1-[[ (3-methylbutyl) amino]carbonyl]butyl]amino]carbonyl]-, ethyl ester, (2S,3S) -
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