CDN1163
CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2, dose-dependently increases the Vmax of SERCA2 Ca2+-ATPase activity in ER microsomes; increases Ca2+-ATPase activity and significantly enhances Ca2+ uptake into the ER, attenuates H2O2-stimulated cell death in HEK cells; improves glucose homeostasis and metabolic parameters, increases glucose tolerance in ob/ob mice; CDN1163 reduces lipid accumulation and decreases lipogenesis in obese mice livers.
Product Specifications
CAS Number
892711-75-0
Product Name Alternative
CDN 1163 | CDN-1163
Purity
>98% (HPLC)
Solubility
DMSO : 50 mg/mL 156.06 mM; H2O : < 0.1 mg/mL
Smiles
O=C (NC1=C2N=C (C) C=CC2=CC=C1) C3=CC=C (OC (C) C) C=C3
Molecular Formula
C20H20N2O2
Molecular Weight
320.392
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (1-Methylethoxy) -N- (2-methyl-8-quinolinyl) benzamide
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