VX-11e
A potent, selective, and orally bioavailable inhibitor of ERK2 with Ki of 200-fold selectivity over GSK3, Aurora A, CDK2, FLT3, etc; significantly inhibits CKAP2 overexpression-induced cell proliferation, migration and invasion in SiHa cells.
Product Specifications
CAS Number
896720-20-0
Product Name Alternative
VX 11e
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (C1=CC (C2=NC (NC3=CC=C (F) C=C3Cl) =NC=C2C) =CN1) N[C@@H] (C4=CC=CC (Cl) =C4) CO
Molecular Formula
C24H20Cl2FN5O2
Molecular Weight
500.3523
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Pyrrole-2-carboxamide, 4-[2-[ (2-chloro-4-fluorophenyl) amino]-5-methyl-4-pyrimidinyl]-N-[ (1S) -1- (3-chlorophenyl) -2-hydroxyethyl]-
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