PF-04929113
PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.
Product Specifications
CAS Number
908115-27-5
Product Name Alternative
SNX-5422
Purity
>98% (HPLC)
Solubility
DMSO:104 mg/mL (199.41 mM) ; Ethanol:5 mg/mL (9.58 mM) ; Water:<1 mg/mL (<1 mM)
Smiles
CC1 (C) CC2=C (C (=NN2C2=CC=C (C (N) =O) C (N[C@H]3CC[C@@H] (CC3) OC (=O) CN) =C2) C (F) (F) F) C (=O) C1 |r, c:6,30, t:4,10,12|
Molecular Formula
C25H30F3N5O4
Molecular Weight
521.53
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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