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OF-1

OF-1 is a potent bromodomain inhibitor that inhibits BRPF1B/2/3 bromodomains with Kd of 0.1/0.5/2.4 uM; displays good selectivity against other bromodomains, 39-fold selectivity over closest off-target BRD4.

Product Specifications

CAS Number

919973-83-4

Product Name Alternative

SGC OF-1 | SGC OF 1 | SGC OF1 | SGCOF1 | SGC-OF-1 | OF-1

Purity

>98% (HPLC)

Solubility

DMSO: 8.8 mg/mL (20 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

O=S (C1=CC=C (Br) C=C1C) (NC2=C (OC) C=C (N3C) C (N (C) C3=O) =C2) =O

Molecular Formula

C17H18BrN3O4S

Molecular Weight

440.312

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4-bromo-N- (6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl) -2-methylbenzenesulfonamide

Available Sizes

Frequently Asked Questions

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