KU-60019 (b)
KU-60019 is an improved analogue of KU-55933, with IC50 of 6.3 nM for ATM in cell-free assays, 270- and 1600-fold more selective for ATM than DNA-PK and ATR, and is a highly effective radiosensitizer.
Product Specifications
CAS Number
925701-49-1
Product Name Alternative
KU60019 | KU 60019 | KU-60019.
Purity
>98% (HPLC)
Solubility
DMSO: 18 mg/mL warmed (32.86 mM)
Smiles
O=C (NC1=CC (CC2=C (C (C3=CC (C=C (N4CCOCC4) O3) =O) =CC=C2) S5) =C5C=C1) CN6C[C@H] (C) O[C@H] (C) C6
Molecular Formula
C30H33N3O5S
Molecular Weight
547.67
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- ((2S,6R) -2,6-dimethylmorpholino) -N- (5- (6-morpholino-4-oxo-4H-pyran-2-yl) -9H-thioxanthen-2-yl) acetamide.
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