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PF 03716556

PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+, K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+, K+-ATPase, used for the treatment of gastroesophageal reflux disease.

Product Specifications

CAS Number

928774-43-0

Purity

>98% (HPLC)

Solubility

Ethanol: 79 mg/mL (200.26 mM) ; DMSO: 79 mg/mL (200.26 mM)

Smiles

CC1=C2[C@@H] (CCOC2=CC=C1) NC3=CC (=CN4C3=NC (=C4) C) C (=O) N (C) CCO

Molecular Formula

C22H26N4O3

Molecular Weight

394.48

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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