TAK-901
A multikinase inhibitor with IC50 of 21 nM and 15 nM for Aurora A/TPX2 and Aurora B/INCENP respectively; inhibits 56 kinases (IC50< 100 nM) ; inhibits kinds of cancer cell lines with EC50s of 40-500 nM; suppresses cellular histone H3 phosphorylation and induced polyploidy.Blood Cancer Phase 1. Discontinued
Product Specifications
CAS Number
934541-31-8
Product Name Alternative
TAK901 | TAK 901
Field of Research
Epigenetics & Chromatin
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (C1=C (C) C2=C (C (C3=CC=CC (S (=O) (CC) =O) =C3) =C1) C4=CC (C) =CN=C4N2) NC5CCN (C) CC5
Molecular Formula
C28H32N4O3S
Molecular Weight
504.6437
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
9H-Pyrido[2,3-b]indole-7-carboxamide, 5-[3- (ethylsulfonyl) phenyl]-3,8-dimethyl-N- (1-methyl-4-piperidinyl) -
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