ARRY380
ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.
Product Specifications
CAS Number
937265-83-3
Product Name Alternative
ARRY-380 analog | ONT380 analog | ONT 380 analog | ONT-380 analog
Purity
>98% (HPLC)
Solubility
DMSO: > 10mM
Smiles
CC1=C (OC2=CC3=NC=NN3C=C2) C=CC (NC2=NC=NC3=C2C=C (C=C3) C2=CC=C (CNCCS (C) (=O) =O) O2) =C1
Molecular Formula
C29H27N7O4S
Molecular Weight
569.63
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6-[5-[[[2- (Methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4- ([1,2,4]triazolo[1,5-a]pyridin-7-yloxy) phenyl]-4-quinazolinamine
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