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ARRY380

ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent against truncated p95-HER2, 500-fold more selective for HER2 versus EGFR.

Product Specifications

CAS Number

937265-83-3

Product Name Alternative

ARRY-380 analog | ONT380 analog | ONT 380 analog | ONT-380 analog

Purity

>98% (HPLC)

Solubility

DMSO: > 10mM

Smiles

CC1=C (OC2=CC3=NC=NN3C=C2) C=CC (NC2=NC=NC3=C2C=C (C=C3) C2=CC=C (CNCCS (C) (=O) =O) O2) =C1

Molecular Formula

C29H27N7O4S

Molecular Weight

569.63

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

6-[5-[[[2- (Methylsulfonyl) ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4- ([1,2,4]triazolo[1,5-a]pyridin-7-yloxy) phenyl]-4-quinazolinamine

Available Sizes

Frequently Asked Questions

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