NVP-BHG712
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Product Specifications
CAS Number
940310-85-0
Product Name Alternative
NVP BHG712 | NVP BHG-712 | NVP BHG 712 | BHG-712 | BHG712
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (NC1=CC=CC (C (F) (F) F) =C1) C2=CC=C (C) C (NC3=C4C (N (C) N=C4) =NC (C5=CC=CN=C5) =N3) =C2
Molecular Formula
C26H20F3N7O
Molecular Weight
503.489
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-methyl-3- (1-methyl-6- (pyridin-3-yl) -1H-pyrazolo[3,4-d]pyrimidin-4-ylamino) -N- (3- (trifluoromethyl) phenyl) benzamide
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