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ISCK03

A specific c-Kit inhibitor that inhibits c-kit phosphorylation in vitro and SCF-induced c-kit phosphorylation in human melanoma cells; also inhibits p44/42 ERK mitogen-activated protein kinase (MAPK) phosphorylation, does not inhibit HGF-induced phosphorylation of p44/42 ERK proteins; induces the dose-dependent depigmentation of newly regrown hair, promotes the depigmentation of UV-induced hyperpigmented spots in vivo; orally acitve.

Product Specifications

CAS Number

945526-43-2

Product Name Alternative

ISCK 03 | ISCK-03

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 38 mg/mL

Smiles

O=S (N (C1=CC=C (C (C) (C) C) C=C1) C2=CC=C (N3C=CN=C3) C=C2) =O

Molecular Formula

C19H21N3O2S

Molecular Weight

355.45394

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Benzenesulfonamide, 4- (1,1-dimethylethyl) -N-[4- (1H-imidazol-1-yl) phenyl]-

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