RAF-IN-10n
A highlt potent and selective BRAF/CRAF inhibitor with IC50 of 24/25 nM, respectively; displays moderate selectivity over p38α (IC50=216 nM) and CAMKII (IC50=822 nM), high selectivity over CDK2, CDK4, PKCa, IKKb, JNK1, MK2, PKA, Src, MKK6, PLK1, p70S6K, PI3 Ka, and PDK1 (IC50>2 uM) .
Product Specifications
CAS Number
950736-05-7
Product Name Alternative
B-RAF IN 1
Field of Research
Neuroscience
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 53 mg/mL
Smiles
O=C (NC1=CC=CC (C2=CC=NC3=C (C4=CC=C (CN (C) C) C=C4) C=NN23) =C1) C5=CC=CC (C (F) (F) F) =C5
Molecular Formula
C29H24F3N5O
Molecular Weight
515.529
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzamide, N-[3-[3-[4-[ (dimethylamino) methyl]phenyl]pyrazolo[1,5-a]pyrimidin-7-yl]phenyl]-3- (trifluoromethyl) -
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