Finasteride
Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM) . (In Vitro) :Finasteride (10 μM; 6-24 h) induces the expression of HO-1 and Nrf2 proteins in PC-3 cells.Finasteride decreases the conversion of [3H]testosterone (T) to [3H]dihydrotestosterone (DHT) in P. crustosum. (In Vivo) :Finasteride (0.1-0.5 mg/kg; p.o. once daily for 16 weeks) reduces prostatic size in dogs with BPH without adversely affecting semen quality or serum testosterone concentration.
Product Specifications
CAS Number
98319-26-7
Product Name Alternative
MK-906 | Propecia | Proscar
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 75 mg/mL (201.32 mM) ; DMSO: 75 mg/mL (201.32 mM)
Smiles
C[C@]12CC[C@H]3[C@@H] (CC[C@@H]4[C@]3 (C) C=CC (N4) =O) [C@@H]1CC[C@@H]2C (NC (C) (C) C) =O
Molecular Formula
C23H36N2O2
Molecular Weight
372.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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