What is the catalog number for MI-773?

The catalog number for MI-773 is HY-17493.

What sizes are available for MI-773?

MI-773 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 50 mg, 100 mg.

How many pack sizes does MI-773 come in?

MI-773 is available in 5 different pack sizes.

MI-773 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MI-773?

MI-773 is manufactured by QuantiMol.

What is the estimated delivery time for MI-773?

Estimated delivery time for MI-773 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MI-773?

The safety data sheet for MI-773 is available here: http://file.medchemexpress.com/batch_PDF/HY-17493/MI-773-SDS-MedChemExpress.pdf.

MI-773

MI-773 is a potent MDM2-p53 protein‐protein interaction (PPI) inhibitor with high binding affinity against MDM2 (Kd=8.2 nM) . MI-773 has antitumor activity[1][2].

Product Specifications

CAS Number

1303607-07-9

UNSPSC

12352005

Hazard Statement

H302, H315, H320, H335

Target

E1/E2/E3 Enzyme; MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/MI-773.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : ≥ 53 mg/mL

Smiles

O=C([C@H](N[C@@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2F)[C@]31C(NC4=C3C=CC(Cl)=C4)=O)N[C@H]5CC[C@H](O)CC5

Molecular Formula

C29H34Cl2FN3O3

Molecular Weight

562.50

Precautions

H302, H315, H320, H335

References & Citations

[1]Zhang Q, et al. Targeting p53-MDM2-MDMX loop for cancer therapy. Subcell Biochem. 2014;85:281-319.|[2]Tatyana A Grigoreva, et al. Amino acids as chiral derivatizing agents for antiproliferative substituted N-benzyl isoindolinones. Chirality. 2018 Jun;30 (6) :785-797.