NSC 86429
SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively) . SU4312 unexpectedly protects against MPP (+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Product Specifications
CAS Number
5812-07-7
Product Name Alternative
SU-4312 | SU 4312 | SU4312. DMBI | NSC 86429
Field of Research
Neuroscience
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (189.16 mM)
Smiles
CN (C) C1=CC=C (C=C1) /C=C\2/C3=CC=CC=C3NC2=O
Molecular Formula
C17H16N2O
Molecular Weight
264.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-[[4- (dimethylamino) phenyl]methylene]-1,3-dihydro-2H-indol-2-one
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