AT-406 HCl
AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins (IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.
Product Specifications
CAS Number
1071992-57-8
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 175 mg/mL (292.55 mM)
Smiles
N12[C@@H] (CCN (C[C@@H] (C1=O) NC (=O) [C@H] (C) NC) C (=O) CC (C) C) CC[C@H]2C (=O) NC (c1ccccc1) c1ccccc1
Molecular Formula
C32H44ClN5O4
Molecular Weight
598.19
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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