What is the catalog number for Fondaparinux sodium?

The catalog number for Fondaparinux sodium is orb1223419.

What sizes are available for Fondaparinux sodium?

Fondaparinux sodium is available in the following size(s): 200 mg, 500 mg, 1 g, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Fondaparinux sodium come in?

Fondaparinux sodium is available in 9 different pack sizes.

Is Fondaparinux sodium in stock?

Fondaparinux sodium is currently made to order / not held in immediate stock. Contact us for lead time.

Fondaparinux sodium

Fondaparinux sodium is a factor Xa inhibitor to form the high affinity binding site for the anti-coagulant factor antithrombin III (ATIII) . (In Vitro) :Fondaparinux sodium is the first agent of a new class of anticoagulants that selectively target factor Xa. For Fondaparinux, its IC50 values (anti-Xa IU/ml) are 0.59±0.05 for activated monocytes (ac-M) and 0.17±0.03 for monocyte-derived microparticles (MMPs) . (In Vivo) :Fondaparinux sodium has a linear, dose-dependent pharmacokinetic profile, which provides a highly predictable response. Fondaparinux sodium is 100% bioavailable, has a rapid onset of action, and has a half-life of 14 to 16 hours, allowing for sustained antithrombotic activity over a 24-hour period. The drug does not affect prothrombin time or activated partial thromboplastin time, nor does it affect platelet function or aggregation.

Product Specifications

CAS Number

114870-03-0

Product Name Alternative

Fondaparinux sodium | PENTA | Arixtra

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

H2O : ≥ 30 mg/mL 17.26 mM

Smiles

[C@H]1 ([C@H] ([C@@H] (O[C@@H]2[C@@H] (O[C@H] ([C@@H] ([C@H]2O) OS (=O) (=O) [O-]) O[C@H]2[C@@H] ([C@H] ([C@H] (O[C@@H]2COS (=O) (=O) [O-]) OC) NS (=O) (=O) [O-]) O) C (=O) [O-]) O[C@@H] ([C@H]1O[C@@H]1O[C@@H] ([C@H] ([C@@H] ([C@H]1O) O) O[C@@H]1[C@@H] ([C@H] ([C@@H] ([C@H] (O1) COS (=O) (=O) [O-]) O) O) NS (=O) (=O) [O-]) C (=O) [O-]) COS (=O) (=O) [O-]) NS (=O) (=O) [O-]) OS (=O) (=O) [O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

Molecular Formula

C31H44N3Na10O49S8

Molecular Weight

1729.09

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Sodium (2S,3S,4R,5R,6R) -6- (((2R,3R,4R,5R,6R) -6- (((2R,3S,4S,5R,6R) -2-carboxylato-4-hydroxy-6- (((2R,3S,4R,5R,6S) -4-hydroxy-6-methoxy-5- (sulfonatoamino) -2- ((sulfonatooxy) methyl) tetrahydro-2H-pyran-3-yl) oxy) -5- (sulfonatooxy) tetrahydro-2H-pyran-3-yl) oxy) -5- (sulfonatoamino) -4- (sulfonatooxy) -2- ((sulfonatooxy) methyl) tetrahydro-2H-pyran-3-yl) oxy) -3- (((2R,3R,4R,5S,6R) -4,5-dihydroxy-3- (sulfonatoamino) -6- ((sulfonatooxy) methyl) tetrahydro-2H-pyran-2-yl) oxy) -4,5-dihydroxytetrahydro-2H-pyran-2-carboxylate