Tyrphostin AG 528
Tyrphostin AG 528 (B66) is a dual inhibitor of EGFR and ErbB2 tyrosine kinases, exhibiting IC50 values of 4.9 μM and 2.1 μM, respectively. It is a research tool used in vitro to study oncogenic signaling pathways and explore potential therapeutic strategies in cancer research, particularly involving the ErbB receptor family.
Product Specifications
CAS Number
133550-49-9
Product Name Alternative
Tyrphostin AG528, Tyrphostin AG-528, Tyrphostin B 66, Tyrphostin B66, Tyrphostin B-66, Tyrphostin AG 528, AG 528, AG528, AG-528, ErbB2, EGFR
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.64% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.53 mM) ; DMSO:55 mg/mL (179.55 mM)
Smiles
Oc1ccc (\C=C (\C#N) C (=O) N2CCc3ccccc23) cc1O
Molecular Formula
C18H14N2O3
Molecular Weight
306.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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