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Preladenant

Preladenant (SCH-420814) is a potent and highly selective adenosine A2A receptor antagonist with a Ki of 1.1 nM and over 1000-fold selectivity versus other adenosine subtypes. This orally bioavailable small molecule is a valuable research tool for investigating Parkinson's disease, both in vitro and in animal models.

Product Specifications

CAS Number

377727-87-2

Product Name Alternative

SCH 420814

Field of Research

Immunology & Inflammation, Neuroscience

Purity

>98%

Bioactivity

Adenosine A2A receptor antagonist

Form

Powder

Solubility

Soluble in DMSO (5 mg/ml with warming)

Smiles

COCCOc1ccc (cc1) N1CCN (CCn2ncc3c2nc (N) n2nc (nc32) -c2ccco2) CC1

Molecular Formula

C25H29N9O3

Molecular Weight

503.57

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

4- (Furan-2-yl) -10-[2-[4-[4- (2-methoxyethoxy) phenyl]piperazin-1-yl]ethyl]-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1 (9),2,4,7,11-pentaen-7-amine

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