AD80
AD80 is a multikinase inhibitor targeting RET, RAF, SRC, and S6K, while exhibiting minimal activity against mTOR. It is utilized in cancer research for investigating signaling pathways and has demonstrated efficacy in both cellular assays and in vivo tumor models.
Product Specifications
CAS Number
1384071-99-1
Product Name Alternative
Raf kinases, Raf, Src, S6 Kinase, S6K, S6Kinase, Ribosomal S6 Kinase (RSK), RET, RET V804L, RET V804M, inhibit, Inhibitor, AD80, AD-80, AD 80, cRET
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
99.49% (May vary between batches)
Solubility
DMSO:60 mg/mL (126.73 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.11 mM)
Smiles
CC (C) n1nc (-c2ccc (NC (=O) Nc3cc (ccc3F) C (F) (F) F) cc2) c2c (N) ncnc12
Molecular Formula
C22H19F4N7O
Molecular Weight
473.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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