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AD80

AD80 is a multikinase inhibitor targeting RET, RAF, SRC, and S6K, while exhibiting minimal activity against mTOR. It is utilized in cancer research for investigating signaling pathways and has demonstrated efficacy in both cellular assays and in vivo tumor models.

Product Specifications

CAS Number

1384071-99-1

Product Name Alternative

Raf kinases, Raf, Src, S6 Kinase, S6K, S6Kinase, Ribosomal S6 Kinase (RSK), RET, RET V804L, RET V804M, inhibit, Inhibitor, AD80, AD-80, AD 80, cRET

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

99.49% (May vary between batches)

Solubility

DMSO:60 mg/mL (126.73 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.11 mM)

Smiles

CC (C) n1nc (-c2ccc (NC (=O) Nc3cc (ccc3F) C (F) (F) F) cc2) c2c (N) ncnc12

Molecular Formula

C22H19F4N7O

Molecular Weight

473.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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