LX2343
LX2343 is a dual-target small molecule inhibitor of BACE1 (IC50 = 11.43±0.36 μM) and a non-ATP competitive PI3K inhibitor (IC50 = 15.99±3.23 μM) . It promotes autophagy, facilitating Aβ clearance in cellular models, making it a useful research tool for studying Alzheimer's disease pathways.
Product Specifications
CAS Number
333745-53-2
Product Name Alternative
BetaAmyloid, Beta Amyloid, Amyloid-β, BACE, BACE1, bAmyloid, Autophagy, b Amyloid, bSecretase, b-Secretase, BetaSecretase, Beta-secretase, Abeta, Inhibitor, inhibit, LX2343, LX-2343, LX 2343, PI3K, Phosphoinositide 3-kinase, β-Secretase, βSecretase, β Amyloid, βAmyloid, β-amyloid peptide
Field of Research
Cell Biology, Neuroscience, Signal Transduction
Purity
99.45% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.21 mM) ; DMSO:55 mg/mL (115.81 mM)
Smiles
COc1ccc (Cl) cc1N (CC (=O) Nc1ccc2OCOc2c1) S (=O) (=O) c1ccccc1
Molecular Formula
C22H19ClN2O6S
Molecular Weight
474.91
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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