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CEP-40783

CEP-40783 (RXDX-106) is a potent and selective oral inhibitor of AXL and c-Met kinases, with additional activity against MER and TYRO3. It is utilized in preclinical cancer research to investigate pathways involved in tumor growth, metastasis, and therapeutic resistance in both cellular and animal models.

Product Specifications

CAS Number

1437321-24-8

Product Name Alternative

CEP 40783, CEP40783, CEP-40783, cMet, c-Met, c-MET, c-Met/HGFR, cMet/HGFR, AXL, Axl, Inhibitor, HGFR, Mer, inhibit, RXDX106, RXDX-106, RXDX 106, TAMReceptor, TAM Receptor, Tyro3

Field of Research

Signal Transduction

Purity

99.45% (May vary between batches)

Solubility

DMSO:5.89 mg/mL (10.01 mM) ; H2O:Insoluble; Ethanol:2 mg/mL (3.4 mM)

Smiles

COc1cc2nccc (Oc3ccc (NC (=O) c4cn (C (C) C) c (=O) n (-c5ccc (F) cc5) c4=O) cc3F) c2cc1OC

Molecular Formula

C31H26F2N4O6

Molecular Weight

588.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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