CEP-40783
CEP-40783 (RXDX-106) is a potent and selective oral inhibitor of AXL and c-Met kinases, with additional activity against MER and TYRO3. It is utilized in preclinical cancer research to investigate pathways involved in tumor growth, metastasis, and therapeutic resistance in both cellular and animal models.
Product Specifications
CAS Number
1437321-24-8
Product Name Alternative
CEP 40783, CEP40783, CEP-40783, cMet, c-Met, c-MET, c-Met/HGFR, cMet/HGFR, AXL, Axl, Inhibitor, HGFR, Mer, inhibit, RXDX106, RXDX-106, RXDX 106, TAMReceptor, TAM Receptor, Tyro3
Field of Research
Signal Transduction
Purity
99.45% (May vary between batches)
Solubility
DMSO:5.89 mg/mL (10.01 mM) ; H2O:Insoluble; Ethanol:2 mg/mL (3.4 mM)
Smiles
COc1cc2nccc (Oc3ccc (NC (=O) c4cn (C (C) C) c (=O) n (-c5ccc (F) cc5) c4=O) cc3F) c2cc1OC
Molecular Formula
C31H26F2N4O6
Molecular Weight
588.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
FBS006-HI 500 mL
FBS - Heat Inactivated Qualified Imported Fetal Bovine Serum (USDA Approved)
Sign In for Pricing
View Details 
TRV-0019280-01 10 µg
Eukaryotic Homing Associated Cell Adhesion Molecule (HCAM)
Sign In for Pricing
View Details TRV-0019280-02 50 µg
Eukaryotic Homing Associated Cell Adhesion Molecule (HCAM)
Sign In for Pricing
View Details TRV-0019280-03 100 µg
Eukaryotic Homing Associated Cell Adhesion Molecule (HCAM)
Sign In for Pricing
View Details TRV-0019280-04 200 µg
Eukaryotic Homing Associated Cell Adhesion Molecule (HCAM)
Sign In for Pricing
View Details