CEP-40783
CEP-40783 (RXDX-106) is a potent and selective oral inhibitor of AXL and c-Met kinases, with additional activity against MER and TYRO3. It is utilized in preclinical cancer research to investigate pathways involved in tumor growth, metastasis, and therapeutic resistance in both cellular and animal models.
Product Specifications
CAS Number
1437321-24-8
Product Name Alternative
CEP 40783, CEP40783, CEP-40783, cMet, c-Met, c-MET, c-Met/HGFR, cMet/HGFR, AXL, Axl, Inhibitor, HGFR, Mer, inhibit, RXDX106, RXDX-106, RXDX 106, TAMReceptor, TAM Receptor, Tyro3
Field of Research
Signal Transduction
Purity
99.45% (May vary between batches)
Solubility
DMSO:5.89 mg/mL (10.01 mM) ; H2O:Insoluble; Ethanol:2 mg/mL (3.4 mM)
Smiles
COc1cc2nccc (Oc3ccc (NC (=O) c4cn (C (C) C) c (=O) n (-c5ccc (F) cc5) c4=O) cc3F) c2cc1OC
Molecular Formula
C31H26F2N4O6
Molecular Weight
588.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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