Sivopixant
Sivopixant (S-600918) is a potent, selective P2X3 receptor antagonist (IC50 = 4.2 nM) with demonstrated analgesic effects. It is a valuable research tool for studying neuropathic pain and chronic cough mechanisms in both in vitro and in vivo models.
Product Specifications
CAS Number
2414285-40-6
Product Name Alternative
Analgesic, Inhibitor, ligation, inhibit, nerve, pain, S 600918, sciatic, S600918, S-600918, Sivopixant, selective, P2XReceptor, P2XRs, P2X Receptor, P2X3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1.67 mg/mL (3.29 mM) ; DMSO:55 mg/mL (108.28 mM)
Smiles
C (N1\C (=N\C2=CC=C (OC3=CC=CC=N3) C=C2) \NC (=O) N (C[C@@H] (C (O) =O) C) C1=O) C4=CC=C (Cl) C=C4
Molecular Formula
C25H22ClN5O5
Molecular Weight
507.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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