ETC-159
ETC-159 is a potent and orally bioavailable small molecule inhibitor of PORCN, demonstrating an IC50 of 2.9 nM in β-catenin pathway reporter assays. It is a valuable research tool for investigating Wnt/β-catenin signaling in various cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
1638250-96-0
Product Name Alternative
Beta-catenin, betacatenin, bcatenin, Inhibitor, ETC 159, ETC 1922159, ETC159, ETC-159, ETC1922159, ETC-1922159, inhibit, Porcupine, Porcn, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin, β-catenin
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
96.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.11 mM) ; DMSO:55 mg/mL (140.53 mM)
Smiles
Cn1c2ncn (CC (=O) Nc3ccc (nn3) -c3ccccc3) c2c (=O) n (C) c1=O
Molecular Formula
C19H17N7O3
Molecular Weight
391.38
Storage Conditions
-20°C
Notes
For research use only.
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