KU-0060648
KU-0060648 is a potent small molecule inhibitor that primarily targets DNA-PK and the PI3Kα, β, and δ isoforms with low nanomolar IC50 values, while showing significantly weaker activity against PI3Kγ. This profile makes it a useful research tool for investigating DNA damage response and PI3K signaling pathways in both cellular and animal models of cancer and other diseases.
Product Specifications
CAS Number
881375-00-4
Product Name Alternative
KU0060648, KU-0060648, KU 0060648, inhibit, mTOR, Inhibitor, Mammalian target of Rapamycin, DNA-dependent protein kinase, DNAPK, DNA-PK, PI3K, PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, Phosphoinositide 3-kinase
Field of Research
Molecular Biology, Signal Transduction
Purity
98.75% (May vary between batches)
Smiles
CCN1CCN (CC (=O) Nc2ccc (-c3cccc4c3oc (cc4=O) N3CCOCC3) c3sc4ccccc4c23) CC1
Molecular Formula
C33H34N4O4S
Molecular Weight
582.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog