ASP5878
ASP5878 is a potent and selective pan-FGFR inhibitor, demonstrating low nanomolar IC50 values against FGFR1-4. This small molecule is a valuable research tool for investigating FGFR-driven signaling in both in vitro biochemical assays and in vivo cancer models, particularly for studying tumorigenesis and potential therapeutic interventions.
Product Specifications
CAS Number
1453208-66-6
Product Name Alternative
Inhibit, Fibroblast growth factor receptor, FGFR, FGFR4, FGFR1, FGFR3, FGFR2, Inhibitor, ASP 5878, ASP-5878, ASP5878
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.80% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.27 mM) ; DMSO:250 mg/mL (613.69 mM)
Smiles
COc1cc (OC) c (F) c (COc2cnc (Nc3cnn (CCO) c3) nc2) c1F
Molecular Formula
C18H19F2N5O4
Molecular Weight
407.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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