Quillaic acid

Quillaic acid (Quillaja sapogenin) It is an anti-gastric cancer and anti-proliferation agent that can promote apoptosis of cancer cells. (apoptosis) . Quillaic acidAlso has analgesic and local anti-inflammatory activity[1][2][3][4].

Product Specifications

CAS Number

[631-01-6]

Product Name Alternative

Quillaja sapogenin

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/quillaic-acid.html

Purity

99.30

Solubility

DMSO : ≥ 41 mg/mL

Smiles

OC([C@]1(CCC(C)(C)C2)[C@]2([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O)[C@@]5(C)C=O)C)[C@]3(C)C[C@H]1O)=O

Molecular Formula

C30H46O5

Molecular Weight

486.68

Precautions

H302, H315, H319, H335

References & Citations

[1]Arrau S, et al. Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. J Ethnopharmacol. 2011 Jan 7;133 (1) :164-7.|[2]Guzmán L, et al. In vitro evaluation and molecular docking of QS-21 and quillaic acid from Quillaja saponaria Molina as gastric cancer agents. Sci Rep. 2020 Jun 29;10 (1) :10534.|[3]Rodríguez-Díaz M, et al. Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. J Pharm Pharmacol. 2011 May;63 (5) :718-24.