Hemin
Hemin chloride is a chlorinated iron porphyrin and a potent inducer of heme oxygenase-1 (HO-1) . It is used therapeutically in acute porphyrias to alleviate heme deficiency and suppress δ-aminolevulinic acid synthetase activity. This compound is widely applied in research models studying oxidative stress, inflammation, and cytoprotection in both cellular and animal studies.
Product Specifications
CAS Number
16009-13-5
Product Name Alternative
Mitophagy, Mitochondrial Autophagy, Ferroptosis, Hemin, Hemin chloride, Autophagy, (HO) -1
Field of Research
Cell Biology
Purity
96.50% (May vary between batches)
Solubility
DMSO:30 mg/mL (46.02 mM) ;0.1M NaOH:25 mg/mL (38.35 mM) ;0.05%DMSO+99.95%PBS:0.33 mg/mL (0.51 mM) ;8% 0.1M NaOH+92% PBS:2 mg/mL (3.07 mM) ;0.05% DMSO+99.95% 0.1 M NaoH:0.33 mg/mL (0.51 mM)
Smiles
[Cl-].[Fe+3].Cc1c (CCC (O) =O) c2cc3[n-]c (cc4nc (cc5[n-]c (cc1n2) c (C=C) c5C) c (C=C) c4C) c (C) c3CCC (O) =O
Molecular Formula
C34H32ClFeN4O4
Molecular Weight
651.94
Storage Conditions
-20°C
Notes
For research use only.
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