Belvarafenib
Belvarafenib (HM95573) is a pan-RAF inhibitor exhibiting potent activity against B-RAF, B-RAF V600E, and C-RAF. It demonstrates antitumor efficacy in preclinical models, supporting its investigation in oncology research for RAF-driven cancers, both in vitro and in vivo.
Product Specifications
CAS Number
1446113-23-0
Product Name Alternative
Belvarafenib, GDC 5573, GDC5573, GDC-5573, Inhibitor, HM95573, HM-95573, HM 95573, inhibit, RG 6185, RG6185, RG-6185, Raf, Raf kinases
Field of Research
Signal Transduction
Purity
≥98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.09 mM) ; DMSO:25 mg/mL (52.2 mM)
Smiles
Cc1ccc2c (Nc3cccc (Cl) c3F) nccc2c1NC (=O) c1csc2c (N) ncnc12
Molecular Formula
C23H16ClFN6OS
Molecular Weight
478.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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