PCPA methyl ester hydrochloride
PCPA methyl ester hydrochloride is a brain-penetrant inhibitor of tryptophan hydroxylase, the rate-limiting enzyme in serotonin biosynthesis. It is widely used in neuroscience research to deplete central 5-HT levels for studying serotonergic function in both in vivo animal models and in vitro cellular systems.
Product Specifications
CAS Number
14173-40-1
Product Name Alternative
Inhibit, Inhibitor, PCPA methyl ester, pCPA methyl ester Hydrochloride, pCPA methyl ester hydrochloride, insomnia, BBB, 5-HT, 5HTReceptor, 5-hydroxytryptamine Receptor, 4-Chloro-DL-phenylalanine methyl ester hydrochloride, 5HT Receptor, 5-HT Receptor, Tryptophan Hydroxylase, Tryptophan hydroxylase, reversible, Serotonin Receptor
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
99.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (19.99 mM) ; DMSO:245 mg/mL (979.53 mM) ; H2O:45 mg/mL (179.91 mM)
Smiles
Cl.COC (=O) [C@@H] (N) Cc1ccc (Cl) cc1
Molecular Formula
C10H13Cl2NO2
Molecular Weight
250.12
Storage Conditions
-20°C
Notes
For research use only.
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