TM5441
TM5441 is an orally active small molecule inhibitor of fibrinogen activator inhibitor-1 (PAI-1) . It exhibits cytotoxic activity against various human cancer cell lines in vitro and has shown efficacy in preclinical models of hypertension and vascular aging. This compound is a research tool for studying oncology, cardiovascular disease, and senescence.
Product Specifications
CAS Number
1190221-43-2
Product Name Alternative
Plasminogen activator inhibitor-1, TM5441, TM-5441, TM 5441, inhibit, Inhibitor, PAI-1, PAI1, Apoptosis
Field of Research
Cell Biology, Metabolism Research
Purity
97.62% (May vary between batches)
Solubility
DMSO:5.67 mg/mL (13.22 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.33 mM)
Smiles
OC (=O) c1cc (Cl) ccc1NC (=O) COCC (=O) Nc1cccc (c1) -c1ccoc1
Molecular Formula
C21H17ClN2O6
Molecular Weight
428.82
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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