VP3.15 dihydrobromide
VP3.15 dihydrobromide is an orally active, brain-penetrant small molecule that potently inhibits both PDE7 and GSK-3 enzymes, with respective IC50 values of 1.59 μM and 0.88 μM. This dual inhibitor is a valuable research tool for investigating neurodegenerative and psychiatric disorders in both cellular and animal models.
Product Specifications
CAS Number
1281681-33-1
Product Name Alternative
Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK-3, GSK3, Inhibitor, inhibit, Phosphodiesterase (PDE), phosphodiesterase, PDE7, VP3.15, VP3.15 dihydrobromide, VP3.15 Dihydrobromide, VP-3.15 dihydrobromide
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
≥95% (May vary between batches)
Solubility
DMSO:22.5 mg/mL (42.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.79 mM)
Smiles
Br.Br.C (CN1CCOCC1) \N=c1 c (-c2ccccc2) n (s1) -c1ccccc1
Molecular Formula
C20H24Br2N4OS
Molecular Weight
528.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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