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VP3.15 dihydrobromide

VP3.15 dihydrobromide is an orally active, brain-penetrant small molecule that potently inhibits both PDE7 and GSK-3 enzymes, with respective IC50 values of 1.59 μM and 0.88 μM. This dual inhibitor is a valuable research tool for investigating neurodegenerative and psychiatric disorders in both cellular and animal models.

Product Specifications

CAS Number

1281681-33-1

Product Name Alternative

Glycogen synthase kinase 3, Glycogen synthase kinase-3, GSK-3, GSK3, Inhibitor, inhibit, Phosphodiesterase (PDE), phosphodiesterase, PDE7, VP3.15, VP3.15 dihydrobromide, VP3.15 Dihydrobromide, VP-3.15 dihydrobromide

Field of Research

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Purity

≥95% (May vary between batches)

Solubility

DMSO:22.5 mg/mL (42.59 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.79 mM)

Smiles

Br.Br.C (CN1CCOCC1) \N=c1 c (-c2ccccc2) n (s1) -c1ccccc1

Molecular Formula

C20H24Br2N4OS

Molecular Weight

528.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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