Triptonide
Triptonide (PG 492) is a bioactive small molecule with demonstrated efficacy in autoimmune disease models and potent antileukemic activity. Its anti-inflammatory function involves upregulating IL-37, a process modulated by ERK1/2 and p38 MAPK signaling pathways, as shown in cellular research.
Product Specifications
CAS Number
38647-11-9
Product Name Alternative
Lymphoma, Lyn, NSC165677, NSC-165677, inhibit, Inhibitor, NSC 165677, ERK, Hook F., beta-catenin, betacatenin, Beta catenin, anti-cancer, Autophagy, Apoptosis, bcatenin, wilfordii, Wnt, PG-492, PG492, PG 492, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, β-catenin, βcatenin, Tripterygium, Triptonide
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.80% (May vary between batches)
Solubility
DMSO:50 mg/mL (139.51 mM)
Smiles
C[C@@]12[C@@]34[C@]5 (C ([C@@]6 ([C@] (O6) ([H]) [C@]3 ([H]) O4) C (C) C) =O) [C@@] (C[C@@]1 ([H]) C7=C (C (OC7) =O) CC2) ([H]) O5
Molecular Formula
C20H22O6
Molecular Weight
358.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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