PF-4800567
PF-4800567 is a potent and selective small molecule inhibitor of casein kinase 1 epsilon (CK1ε), exhibiting an IC50 of 32 nM with over 20-fold selectivity against the closely related CK1δ isoform. This tool compound is used in research to investigate circadian rhythms, Wnt/β-catenin signaling, and neurodegenerative diseases in both cellular and animal models.
Product Specifications
CAS Number
1188296-52-7
Product Name Alternative
CK1ε, CaseinKinase, Casein Kinase, inhibit, Inhibitor, PF 4800567, PF-4800567, PF4800567
Field of Research
Metabolism Research, Stem Cell & Developmental Biology
Purity
98.23% (May vary between batches)
Solubility
DMSO:60 mg/mL (166.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.56 mM)
Smiles
Nc1ncnc2n (nc (COc3cccc (Cl) c3) c12) C1CCOCC1
Molecular Formula
C17H18ClN5O2
Molecular Weight
359.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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