Azd1390
AZD1390 is a highly potent and selective ATM kinase inhibitor, exhibiting an IC50 of 0.78 nM in cellular assays and >10,000-fold selectivity over related PIKK family members. It is a valuable chemical probe for investigating ATM's role in DNA damage response pathways in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
2089288-03-7
Product Name Alternative
Ataxia telangiectasia mutated, ATM/ATR, ATM, ATM and RAD3 related, AZD 1390, azd1390, azd-1390, ATR, inhibit, Inhibitor
Field of Research
Molecular Biology, Signal Transduction
Purity
97.41% (May vary between batches)
Solubility
DMSO:4.84 mg/mL (10.13 mM)
Smiles
CC (C) n1c2c (cnc3cc (F) c (cc23) -c2ccc (OCCCN3CCCCC3) nc2) n (C) c1=O
Molecular Formula
C27H32FN5O2
Molecular Weight
477.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Cr6320-500gEcoli 500 µg (E. coli)
Recombinant Staphylococcus Aureus SaurJH9_1150 Protein (aa 1-72)
Sign In for Pricing
View Details 
MBS6479677-01 0.2 mL
HSPA4L, CT (Heat shock 70-related protein APG-1, Osmotic stress protein 94, Heat shock 70kD protein 4L, HSPA4L, APG1, OSP94) (FITC)
Sign In for Pricing
View Details MBS6479677-02 5x 0.2 mL
HSPA4L, CT (Heat shock 70-related protein APG-1, Osmotic stress protein 94, Heat shock 70kD protein 4L, HSPA4L, APG1, OSP94) (FITC)
Sign In for Pricing
View Details