WZ8040
WZ8040 is a novel, irreversible EGFR inhibitor that selectively targets the T790M mutant while sparing ERBB2 phosphorylation (T798I) . It is a valuable research tool for studying resistant non-small cell lung cancer in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1214265-57-2
Product Name Alternative
ErbB-1, Epidermal growth factor receptor, EGFR (T790M), EGFR, Inhibitor, HER1, mutated, inhibit, NSCLC, WZ 8040, WZ8040, WZ-8040, phosphorylation
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.42% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.16 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:3 mg/mL (6.24 mM) ; DMSO:89 mg/mL (185.03 mM)
Smiles
CN1CCN (CC1) c1ccc (Nc2ncc (Cl) c (Sc3cccc (NC (=O) C=C) c3) n2) cc1
Molecular Formula
C24H25ClN6OS
Molecular Weight
481.01
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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