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FLLL32

FLLL32 is a potent small molecule inhibitor of the JAK2/STAT3 signaling pathway, demonstrating an IC50 value below 5 μM. It is widely used in biochemical and cellular research to study oncogenesis, inflammation, and immune responses, with applications in both in vitro assays and in vivo animal models of cancer.

Product Specifications

CAS Number

1226895-15-3

Product Name Alternative

Inhibitor, FLLL 32, FLLL32, FLLL-32, inhibit, JAK, JAK2, Janus kinase, Apoptosis, STAT

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

96.39% (May vary between batches)

Solubility

DMSO:85 mg/mL (182.97 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.1 mM) ; Ethanol:24 mg/mL (51.66 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

COc1ccc (\C=C\C (=O) C2 (CCCCC2) C (=O) \C=C\c2ccc (OC) c (OC) c2) cc1OC

Molecular Formula

C28H32O6

Molecular Weight

464.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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