Uprosertib

Uprosertib (GSK2141795) is a broad-spectrum, ATP-competitive Akt inhibitor with IC50 values of 180, 328, and 38 nM for Akt1, Akt2, and Akt3, respectively. It is a research tool used in vitro and in vivo to study PI3K/Akt pathway signaling in oncology and metabolic disease research.

Product Specifications

CAS Number

1047634-65-0

Product Name Alternative

Inhibit, GSK795, GSK-795, GSK 2141795, GSK 795, GSK2141795, GSK-2141795, Inhibitor, Akt, Akt3, Akt2, Akt1, Protein kinase B, PKB, Uprosertib

Field of Research

Signal Transduction

Purity

95.10% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.66 mM) ; Ethanol:76 mg/mL (177.05 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:65 mg/mL (151.43 mM)