KY-226
KY-226 is a potent and selective small molecule inhibitor of PTP1B, exhibiting an IC50 of 0.25 μM. It serves as a valuable research tool for studying type 2 diabetes and obesity in both cellular and animal models, based on its role in insulin and leptin signaling pathways.
Product Specifications
CAS Number
1621673-53-7
Product Name Alternative
LPS, neurons, KY226, KY-226, KY 226, inhibit, Inhibitor, insulin, leptin, anti-obesity, anti-diabetic, Akt, phosphorylated, Phosphatase, PTP1B, ZO-1
Field of Research
Metabolism Research
Purity
96.64% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.15 mM) ; DMSO:25 mg/mL (51.9 mM)
Smiles
CCCCCCS (=O) (=O) NC (=O) c1ccc (CSCc2ccc (cc2) -c2ccccc2) cc1
Molecular Formula
C27H31NO3S2
Molecular Weight
481.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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