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Nelfinavir

Nelfinavir (AG1341) is a potent HIV-1 protease inhibitor (Ki=2 nM) used in antiretroviral therapy. Research has also investigated its broad-spectrum anticancer properties in vitro, including the induction of endoplasmic reticulum stress and the inhibition of tumor cell proliferation in various cancer models.

Product Specifications

CAS Number

159989-64-7

Product Name Alternative

Human immunodeficiency virus, Inhibitor, HIV, HIV Protease, HIV-1, HIVProtease, myeloma, multiple, infection, inhibit, Nelfinavir, AG 1341, AG1341, AG-1341, cells, proliferation, protease, production, phosphorylation

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

98.05% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (7.04 mM) ; DMSO:100 mg/mL (176.12 mM)

Smiles

Cc1c (O) cccc1C (=O) N[C@@H] (CSc1ccccc1) [C@H] (O) CN1C[C@H]2CCCC[C@H]2C[C@H]1C (=O) NC (C) (C) C

Molecular Formula

C32H45N3O4S

Molecular Weight

567.78

Storage Conditions

-20°C

Notes

For research use only.

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