BIO-32546
BIO-32546 (example 12b, S-isomer) is an autotaxin (ATX) modulator (IC50: 1 nM), extracted from the patent US20170158687A1[1].
Product Specifications
CAS Number
1548743-66-3
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bio-32546.html
Purity
99.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(F)(C1=C(O[C@@H]2CC[C@@H](CC2)C(F)(F)F)C=CC3=C1C=C([C@@H](N4C5CC(CC4CC5)C(O)=O)C)C=C3)F
Molecular Formula
C28H31F6NO3
Molecular Weight
543.54
References & Citations
[1]Kevin M. Guckian, et al. Atx modulating agents. Patent. US20170158687A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Autotaxin
Available Sizes
Frequently Asked Questions
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