BYK204165
BYK204165 (RT-017290) is a potent small molecule inhibitor of PARP1, demonstrating an IC50 of 44.67 nM against the human recombinant enzyme. This compound is a valuable research tool for investigating DNA repair mechanisms in oncology, with applications in both in vitro cellular assays and in vivo preclinical cancer models.
Product Specifications
CAS Number
1104546-89-5
Product Name Alternative
Antitumor, BYK 204165, BYK204165, BYK-204165, Inhibitor, inhibit, PARP, RT 017290, RT017290, RT-017290, poly ADP ribose polymerase
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
95.09% (May vary between batches)
Solubility
DMSO:125 mg/mL (495.5 mM)
Smiles
Cn1cccc1\C=C1\C (=O) NC (=O) c2ccccc12
Molecular Formula
C15H12N2O2
Molecular Weight
252.27
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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