AEM1
AEM1 is a small molecule inhibitor that suppresses oncogenic NRF2 signaling. It downregulates NRF2 target genes, enhancing chemosensitivity in A549 lung cancer cells and impeding tumor growth in both cell culture and animal models, supporting its use in cancer therapeutics research.
Product Specifications
CAS Number
1030123-90-0
Product Name Alternative
AEM 1, AEM1, AEM-1, Inhibitor, NRF2, Keap1-Nrf2, inhibit
Field of Research
Immunology & Inflammation
Purity
97.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.27 mM) ; DMSO:30 mg/mL (79.07 mM)
Smiles
FC1=CC=C (C=C1) C1=CSC2=C1C (NCC1=CC=C3OCOC3=C1) =NC=N2
Molecular Formula
C20H14FN3O2S
Molecular Weight
379.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog