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GSK620

GSK620 is a highly selective pan-BD2 BET inhibitor demonstrating potent anti-inflammatory activity in human whole blood assays. Its excellent selectivity profile and favorable oral pharmacokinetics support its use for in vivo research into inflammation and oncology, where BET bromodomain function is implicated.

Product Specifications

CAS Number

2088410-46-0

Product Name Alternative

Anti-inflammatory, blood, human, GSK 620, GSK620, GSK-620, EpigeneticReaderDomain, Epigenetic Reader Domain, oral, pan-BD2, inhibit, Inhibitor, phenotype, whole, selectivity

Field of Research

Epigenetics & Chromatin

Purity

99.05% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (10.14 mM) ; DMSO:45 mg/mL (138.31 mM)

Smiles

CNC (=O) c1cc (cn (Cc2ccccc2) c1=O) C (=O) NC1CC1

Molecular Formula

C18H19N3O3

Molecular Weight

325.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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