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MGH-CP1

MGH-CP1 is a potent, selective inhibitor of TEAD palmitoylation, effectively blocking TEAD2 and TEAD4 auto-palmitoylation in vitro with IC50 values of 710 nM and 672 nM, respectively. This compound is a valuable chemical probe for investigating Hippo signaling pathway biology in cancer research and cellular models.

Product Specifications

CAS Number

896657-58-2

Product Name Alternative

MGH CP1, MGHCP1, MGH-CP1, MGH-CP-1, inhibit, Myc, Epithelial, Lats1/2 deletion, Inhibitor, Apoptosis, TEAD auto-palmitoylation, TEAD2, TEAD4, TEAD

Field of Research

Cell Biology

Purity

98.66% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.43 mM) ; Ethanol:74 mg/mL (200.81 mM) ; DMSO:45 mg/mL (122.12 mM)

Smiles

O=C (CSc1ncn[nH]1) Nc1ccc (cc1) C12CC3CC (CC (C3) C1) C2

Molecular Formula

C20H24N4OS

Molecular Weight

368.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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