AS1810722
AS1810722 is a potent, orally bioavailable STAT6 inhibitor with an IC50 of 1.9 nM. This fused bicyclic pyrimidine also inhibits CYP3A4 and is a valuable research tool for studying STAT6-driven pathologies, including allergic asthma and atopic dermatitis, in both cellular and animal models.
Product Specifications
CAS Number
909561-15-5
Product Name Alternative
STAT, STAT6, CYPs, CYP3A4, Cytochrome P450, allergic, AS1810722, AS-1810722, AS 1810722, asthma, orally, infiltration, IL-4, inhibit, Inhibitor, IFN-γ, eosinophil
Field of Research
Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.13% (May vary between batches)
Solubility
DMSO:62.5 mg/mL (130.89 mM)
Smiles
NC (=O) CN1CCN (CC1) c1ccc (Nc2ncc3ccn (Cc4cc (F) cc (F) c4) c3n2) cc1
Molecular Formula
C25H25F2N7O
Molecular Weight
477.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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